Microalgal-based bioremediation has become a viable alternative to conventional physical/chemical treatment methods for removing toxic metals and minerals as it provides a sustainable pathway to treat many wastewater streams. Lead (Pb) is one of the toxic and invasive heavy metal (HM) which is released into wastewater by various industries. Consuming Pb poses risks to humans even in lower concentrations, and effects go up to the damage to the central nervous system and brain function. This study aims to evaluate the potential of using a thermophilic acidophilic red alga, Galdieria sulphuraria (GS) to remove/recover Pb from industrial wastewater. The microalga GS thrives between pH 0.5–4.0 and temperatures up to 56°C and demonstrated growth in municipal wastewater for bioremediation applications in multiple past studies. Three different concentrations (1.25 mg/L, 2.50 mg/L, and 5.00 mg/L) of Pb were introduced into the algal growth media in the single metal solution system. The test was carried out for 7 days. Results indicated that the growth decreased until the second day in the Pb-containing growth media and increased up to the fifth day. The corresponding ammonia and phosphorus level in the growth media also went down in the system on the seventh day of the experiment. Further, ICP-AES was used to analyze the metals in the supernatant to determine whether Galdieria sulphuraria could effectively bioremediate the Pb. Results showed that the Galdieria sulphuraria effectively sorbed Pb in the media containing 1.25 mg/L and 2.50 mg/L of Pb whereas no Pb sorption was seen in the growth media having 5.00 mg/L of Pb. These initial results provided encouraging results for the bioremediation of Pb using Galdieria sulphuraria