The ongoing coronavirus (COVID-19), inducing more than 290.6 million cases worldwide, is highly contagious and is capable of presenting numerous health implications. COVID-19 can range from contributing asymptomatic to life-threatening symptoms. While mainly involving the respiratory system, it can affect almost every organ of the body, including the eye. Patients with COVID-19 may present or develop ophthalmic disease and symptoms. Literature was acquired from PubMed, Google Scholar, and Centers for Disease Prevention and Control (CDC) using the following search terms: COVID-19, SARS CoV-2, ophthalmic viral manifestations, adenovirus, influenza, conjunctivitis, keratitis, retinitis, HSV-1, and herpes simplex keratitis. COVID-19 induced ophthalmic manifestations and diseases include conjunctivitis, ocular irritation, and discharge. Other viral infections causing ophthalmic disease can include keratoconjunctivitis corneal blindness, herpes simplex keratitis, necrotizing retinitis, and petechial conjunctival hemorrhages. Although a portion of the mechanisms behind ophthalmic disorders among the studied viral infections are corresponding, the frequency and severity of eye symptoms differ. Viral mechanisms associated with eye infections are similar but differ in severity, duration, and symptoms, potentially due to the increased pro-inflammatory cytokines activated by COVID-19. COVID-19 also differs from other viral manifestations due to angiotensin-converting enzyme 2 (ACE2) receptor expression in conjunctival epithelial cells, allowing for entry of the virus in human host cells and a difference in cytokine response when compared to other cytokine release syndrome (CRS) viruses.